Hypoxia-responsive CEA-targeted CAR T cells in CEA-positive solid tumors through intraperitoneal or intravenous infusion: a phase 1 trial

Nature Cancer 2026

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Authors: Yang Gao, Jie Li, Hangyu Zhang, Yingzi Zhang, Siyuan Qian, Xudong Zhu, Libing Hong, Li Xie, Qihan Fu, Xuanwen Bao, Zhou Tong, Yunyan Li
+13 more Bin Li, Linling Wang, Junjie Shen, Qianzhen Zhang, Xiao He, Yi Zheng, Chao Yao, Lulu Liu, Peng Zhao, Pedro Villarejo Campos, Zhi Yang, Cheng Qian, Weijia Fang
DOI: 10.1038/s43018-026-01124-3
Cited by: 7
References: 41

Fields of Study & Subjects

CAR-T cell therapy research Immune Cell Function and Interaction Monoclonal and Polyclonal Antibodies Research

Publication details

Journal / source
Nature Cancer
Publisher
Springer Science and Business Media LLC
Volume
7
Issue
4
Pages
608–621
Publication date
27 February 2026
Language
EN