A high-MAPK, low-WNT cell state drives metastatic dissemination in colorectal cancer

Nature Cancer 2026

View at publisher
Authors: Melanie Heinlein, Ginny Li, Noelyn Kljavin, Amanda R. Moore, Brian Biehs, Liming Tao, Soufiane Boumahdi, Farnaz Mohammadi, Minyi Shi, Yuxin Liang, Hartmut Koeppen, Nicolò Riggi
+2 more Robert Piskol, Frédéric J. de Sauvage
DOI: 10.1038/s43018-026-01155-w
Cited by: 4
References: 78

Fields of Study & Subjects

Wnt/β-catenin signaling in development and cancer Cancer Cells and Metastasis Melanoma and MAPK Pathways

Publication details

Journal / source
Nature Cancer
Publisher
Springer Science and Business Media LLC
Volume
7
Issue
6
Pages
899–914
Publication date
7 May 2026
Language
EN