Gemcitabine and nab-paclitaxel with or without the VDR agonist paricalcitol for metastatic pancreatic cancer: a randomized, multiarm, run-in phase trial

Nature Cancer 2026 Open access

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Authors: Kimberly J. Perez, Andressa Dias Costa, Alexander Jordan, Thomas B. Karasic, Dalia Elganainy, Suryun Kim, Chen Yuan, Dan Y. Gui, Runzi Tan, Sung Chul Hong, X Wang, Simona Cristea
+34 more Emma Coleman, Morgan Truitt, Tae Gyu Oh, Hui Zheng, C. Sloane Furniss, Lauren Brais, Alexandra Bird, Josh Remland, Vasilena Gocheva, Jennifer S. Thalappillil, Mark Anderson, James M. Cleary, Andrea Enzinger, Marios Giannakis, Kimmie Ng, Douglas Adam Rubinson, Benjamin Schlechter, Rishi Surana, Harshabad Singh, Thomas Abrams, Ursina R. Teitelbaum, Natallia Izgur, Eliezer Allen, Peter S. Winter, Srivatsan Raghavan, J J Yeh, Daniel Von Hoff, Christopher Liddle, Michael Downes, Ronald M. Evans, PETER O'DWYER, Andrew Aguirre, Jonathan A. Nowak, Brian Matthew Wolpin
DOI: 10.1038/s43018-026-01165-8
Cited by: 1
References: 65

Fields of Study & Subjects

Vitamin D Research Studies Pancreatic and Hepatic Oncology Research Cancer Research and Treatments

Publication details

Journal / source
Nature Cancer
Publisher
Springer Science and Business Media LLC
Volume
7
Issue
6
Pages
928–943
Publication date
25 May 2026
Language
EN