PAPOLA-mediated hyperactive polyadenylation promotes leukemogenesis and leukemia stem cell self-renewal through metabolic reprogramming

Nature Cancer 2026

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Authors: Siyao Guo, Yutong Zou, Canfeng Zhang, Hui Han, Yishan Li, Yucong Sun, Zhaoyu Wang, Wanrui Zhang, Jiang Zhang, Yuli Gan, Qiang Zhang, Jieyi Ma
+7 more Siyi Zheng, Hongshen Qiu, Yan Zhu, Wange Lu, Yong Bao, Meng Zhao, Shuibin Lin
DOI: 10.1038/s43018-026-01190-7
Cited by: 1
References: 55

Fields of Study & Subjects

RNA Research and Splicing Cancer Hypoxia and Metabolism Nuclear Structure and Function

Publication details

Journal / source
Nature Cancer
Publisher
Springer Science and Business Media LLC
Volume
7
Issue
8
Pages
1208–1226
Publication date
15 July 2026
Language
EN