The glycolytic metabolite phosphoenolpyruvate restricts cGAS-driven inflammation to promote healthy aging

Nature Aging 2026

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Authors: Zengqing Song, Huaibin Hu, Wanpeng Zhang, Xincheng Zheng, Liyun Liang, Bing Zhao, Guangping Song, Jianing Li, Sen Li, Yuqi Wen, Biyu Zhang, Wen Wang
+7 more Guozhen Deng, Cun‐Jin Zhang, Hua Jiang, Supei Hu, Haiqing Tu, Min Wu, H. Li
DOI: 10.1038/s43587-026-01087-1
Cited by: 5
References: 62

Fields of Study & Subjects

interferon and immune responses Immune responses and vaccinations HIV Research and Treatment

Publication details

Journal / source
Nature Aging
Publisher
Springer Science and Business Media LLC
Volume
6
Issue
4
Pages
831–848
Publication date
6 March 2026
Language
EN