Hypoxia-induced autophagic degradation of HIF-1α attenuates cellular aging and extends mammalian lifespan

Nature Aging 2026

View at publisher
Authors: Chen Yang, Zeng Xu, S T He, Gen-Jiang Zheng, Jian‐xi Wang, Fa-Zhi Zang, HU Jin-quan, Yun‐Hao Wang, Wen-Yu Zhang, Chen-Fei Gao, Tianshuai Zhang, Ye Yang
+15 more Hao Chen, Hao Chen, Fanqi Kong, Xiao Lv, Lei Liang, Yue-Li Sun, Zi-Xi Wang, Zi-Xi Wang, Peng Cao, Xiao-Dong Wu, Bo Gao, Ye Tian, Bo Hu, Hua-Jiang Chen, Hua-Jiang Chen
DOI: 10.1038/s43587-026-01124-z
Cited by: 1
References: 89

Fields of Study & Subjects

Autophagy in Disease and Therapy Cancer Hypoxia and Metabolism Spine and Intervertebral Disc Pathology

Publication details

Journal / source
Nature Aging
Publisher
Springer Science and Business Media LLC
Volume
6
Issue
5
Pages
1021–1041
Publication date
12 May 2026
Language
EN