Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging

Nature Aging 2026

View at publisher
Authors: Min Lei, Zhenye Zhu, Huihui Xie, Chenlu Wei, Jiajia Zhu, Keer Wang, Kexin Zhang (301752), Yongxing Yu, Linli Yang, Xiangyang Zhang, Ning Song, Diyi Xie
+5 more Ruizhi Guo, Yanqing Zhao, Aaron J. W. Hsueh, Yingpu Sun, Qingling Yang
DOI: 10.1038/s43587-026-01195-y
Cited by: 1
References: 74

Fields of Study & Subjects

interferon and immune responses Cytokine Signaling Pathways and Interactions Endoplasmic Reticulum Stress and Disease

Publication details

Journal / source
Nature Aging
Publisher
Springer Science and Business Media LLC
Volume
6
Issue
9
Pages
1866–1885
Publication date
28 August 2026
Language
EN