Commentary: With Regards to the WISDOM trial
Abstract
Risk-based screening includes varying screening protocols for women based on their risk of breast cancer. The WISDOM trial incorporates universal genetic testing for nine susceptibility genes into risk assessment. Carriers of high-penetrance mutations are offered an annual MRI. One-third of the women with a mutation would not have qualified for genetic testing based on traditional criteria.
Fields of Study & Subjects
BRCA gene mutations in cancer
MRI in cancer diagnosis
Breast Cancer Treatment Studies
Publication details
- Journal / source
- BJC Reports
- Publisher
- Springer Science and Business Media LLC
- Volume
- 4
- Issue
- 1
- Publication date
- 23 March 2026
- Language
- EN