Rethinking endometriosis recurrence: from clinical challenge to biological opportunity
Abstract
Endometriosis postoperative recurrence remains a major clinical challenge and a poorly understood biological process, directly impacting long-term care. This narrative review integrates current knowledge on recurrence definitions, patterns, risk factors, and prevention strategies; potential predictive models and candidate biomarkers; and surgical and biological contributors to recurrence. We propose that recurrent endometriosis represents a valuable model that may help uncover disease mechanisms and guide future research toward personalized, mechanism-based management strategies.
Fields of Study & Subjects
Endometriosis Research and Treatment
Connective Tissue Growth Factor Research
Coagulation
Bradykinin
Polyphosphates
and Angioedema
Publication details
- Journal / source
- npj Women s Health
- Publisher
- Springer Science and Business Media LLC
- Volume
- 4
- Issue
- 1
- Publication date
- 14 January 2026
- Language
- EN