The state of imaging glycolytic metabolism in cancer with magnetic resonance

npj Imaging 2026 Open access

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Authors: Mario C. Chang, Matthew E. Merritt, Kayvan R. Keshari
DOI: 10.1038/s44303-026-00146-x
Cited by: 0
References: 76

Abstract

Imaging is essential for probing cancer biology and tumor surveillance in humans. Combining isotopically labeled substrates with advanced imaging approaches yields a new platform, metabolic imaging. Although cancer metabolism research began ~100 years ago, breakthroughs in magnetic resonance imaging (MRI) like hyperpolarization, deuterium metabolic imaging, and novel probes have revolutionized our ability to appreciate deregulated glycolysis in cancer. Here, we discuss the state and future of glycolytic imaging with MRI.

Fields of Study & Subjects

Cancer Hypoxia and Metabolism Advanced NMR Techniques and Applications Advanced MRI Techniques and Applications

Publication details

Journal / source
npj Imaging
Volume
4
Issue
1
Pages
9–9
Publication date
10 February 2026
Language
EN