Prioritizing shared neoantigens profiling across analytical platforms for an inclusive cancer immunotherapy: from bench to the point-of-care frontier

npj Biosensing 2026 Open access

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Authors: Erika Castrignanò, Eleonora Macchia, Valentina Morciano, Paolo Bollella, Alessandra Costantino, Valentina Mongelli, Lucia Sarcina, Ilaria Iacobellis, Mariapia Caputo, Francesco Leonetti, Luisa Torsi
DOI: 10.1038/s44328-026-00111-z
Cited by: 1
References: 243

Abstract

Shared neoantigens and cancer-related biomarkers are suitable biomolecules with the potential to pursue equitable cancer early diagnosis and immunotherapy at large scale. This review outlines the current repertoire on shared neoantigens and critically assesses the landscape of analytical platforms for their profiling, with a focus on their translation from laboratory-scale systems to emerging single-molecule detection technologies, paving the way toward point-of-care testing as the ultimate ultrasensitive analytical strategy with significant scalability.

Fields of Study & Subjects

Advanced biosensing and bioanalysis techniques Advanced Biosensing Techniques and Applications Monoclonal and Polyclonal Antibodies Research

Publication details

Journal / source
npj Biosensing
Publisher
Springer Science and Business Media LLC
Volume
3
Issue
1
Publication date
30 July 2026
Language
EN