Rethinking sepsis prediction in the era of large language models

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Authors: Andrew Wong, Karandeep Singh, Shamim Nemati
Cited by: 2
References: 44

Abstract

Automated sepsis prediction models have historically struggled due to the heterogenous clinical presentation of sepsis. Unlike traditional methods, large language models (LLMs) offer a novel way to integrate clinical context from text-based data into clinical prediction tasks, leading to recent groundbreaking performance in sepsis prediction. As LLMs become increasingly powerful, health systems must rethink their approach to clinical and data workflows to effectively integrate LLMs into their clinical environments.

Fields of Study & Subjects

Sepsis Diagnosis and Treatment Machine Learning in Healthcare Artificial Intelligence in Healthcare and Education

Publication details

Journal / source
npj Health Systems
Publisher
Springer Science and Business Media LLC
Volume
3
Issue
1
Publication date
9 January 2026
Language
EN