Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing

Lab on a Chip 2026 Open access

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Authors: Callum D. Hay, Suchaya M. Mahuttanatan, Colin Patrick Pilkington, Miguel Paez-Perez, Kimberly Kelly, Yuval Elani, Marina K. Kuimova, Nicholas J. Brooks, Michela Noseda, James W. Hindley, Oscar Ces
DOI: 10.1039/d3lc00995e
Cited by: 3
References: 70

Abstract

targeted delivery, showcasing the potential of our device to produce formulations for therapeutic delivery. As a flow-based method, VFF can facilitate rapid formulation investigation and produce large sample volumes for cell-based validation studies, whilst avoiding inter-batch sample variation. Furthermore, the accessible nature of this VFF approach will help to democratise millifluidics, facilitating the wider adoption of flow-based production methods to develop nanomedical formulations.

Fields of Study & Subjects

Pickering emulsions and particle stabilization Lipid Membrane Structure and Behavior Advancements in Transdermal Drug Delivery

Publication details

Journal / source
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC)
Volume
26
Issue
3
Pages
635–649
Publication date
1 January 2026
Language
EN