Targeted serum metabolomics reveals alterations in amino acid and neurotransmitter pathways in Parkinson's disease

The Analyst 2026

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Authors: Jiaxin Yang, Dong Wu, Zhiwei Wang, Jichun Zhang, Xiaowen Zheng, Sheng Wang, Fen Huang, Shuai Song, Huan Yu
DOI: 10.1039/d5an00961h
Cited by: 2
References: 39

Abstract

= 0.013). These findings indicate that PD is associated with pronounced disruptions in serum amino acid and neurotransmitter metabolism. The cross-talk between these pathways offers new insights into PD pathogenesis.

Fields of Study & Subjects

Metabolomics and Mass Spectrometry Studies Parkinson's Disease Mechanisms and Treatments Diet and metabolism studies

Publication details

Journal / source
The Analyst
Publisher
Royal Society of Chemistry (RSC)
Volume
151
Issue
6
Pages
1639–1649
Publication date
1 January 2026
Language
EN