Integrated microfluidic device for rapid and accurate point-of-care detection of high-risk HPV16 and HPV18

The Analyst 2026

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Authors: Natish Kumar, Monika Kumari, Devtulya Chander, Sandeep Dogra, Asha Chaubey, Ravi Kumar Arun
DOI: 10.1039/d5an01244a
Cited by: 2
References: 19

Abstract

to 1 copy per µL. A clinical evaluation of 50 cervical swab samples yielded a sensitivity of 96.8% and a specificity of 100% compared to qPCR, with positive and negative predictive values of 100% and 94.7%, respectively. The platform's portability, low cost, and minimal user intervention make it an ideal solution for decentralized settings, offering a transformative approach to early HPV screening and cervical cancer prevention in resource-limited environments.

Fields of Study & Subjects

Biosensors and Analytical Detection Microfluidic and Capillary Electrophoresis Applications Microfluidic and Bio-sensing Technologies

Publication details

Journal / source
The Analyst
Publisher
Royal Society of Chemistry (RSC)
Volume
151
Issue
5
Pages
1371–1386
Publication date
1 January 2026
Language
EN