A neutral BODIPY molecular rotor photosensitizer for mitochondrial targeting

The Analyst 2026

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Authors: Surendra Kumar, Anjani Kumar, Durgendra Yadav, Sathya prakash Kumarasamy, Vinay Sharma, Roop Shikha Singh
DOI: 10.1039/d5an01314c
Cited by: 1
References: 21

Abstract

Herein, two novel neutral sulfone-BODIPY-based molecular rotors (SB1 and SB2) have been designed and synthesized, integrating viscosity-responsive turn-on fluorescence with ISC-driven ROS generation. The sulfone group acted as a strong electron acceptor to enhance ICT, while phenyl conjugation imparted fluorescence sensitivity through restricted rotation. These neutral sulfone-BODIPYs enable mitochondrial targeting and imaging and serve as potential photosensitizers for biomedical applications.

Fields of Study & Subjects

Luminescence and Fluorescent Materials Molecular Sensors and Ion Detection Supramolecular Chemistry and Complexes

Publication details

Journal / source
The Analyst
Publisher
Royal Society of Chemistry (RSC)
Volume
151
Issue
8
Pages
2161–2165
Publication date
1 January 2026
Language
EN