Comprehensive database enables the UHPLC-Q-orbitrap-MS/MS method to discover 16 “overlooked” compounds and supply three new pharmacopoeia quality-markers for charred Semen Arecae ( Jiaobinglang )
Abstract
: sixteen "overlooked" compounds were found in CSA for the first time by database-affinity UHPLC-Q-orbitrap-MS/MS. Three supplemental Q-markers were integrated with arecoline to develop a new pharmacopeia Q-marker system. The system can overcome the limitations of the old and risky Q-marker (arecoline). This successful attempt indicates that a comprehensive database can enable UHPLC-Q-orbitrap-MS/MS for the in-depth analysis of Chinese herbal medicines and quality-control update of charred CHMs.
Fields of Study & Subjects
Traditional Chinese Medicine Analysis
Plant-based Medicinal Research
Andrographolide Research and Applications
Publication details
- Journal / source
- Analytical Methods
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 5
- Pages
- 1149–1163
- Publication date
- 1 January 2026
- Language
- EN