Dynamic multiple reaction monitoring for high throughput detection and quantitation of polycyclic aromatic compounds

Analytical Methods 2026

View at publisher
Authors: Zhe Xia, Thor H. J. Halldorson, Nipuni N. Vitharana, Marcus Kim, Dami Daramola, Chris H. Märvin, Philippe J. Thomas, Reyd A. Smith, Jennifer Francoise Provencher, Gregg T. Tomy
DOI: 10.1039/d5ay01950h
Cited by: 0
References: 24

Abstract

. The dMRM method achieved comparable or improved precision and accuracy compared to conventional MRM for less complex matrices, such as standard solutions and biota. Negative systematic biases were observed for a subset of analytes in the sediment matrix for both approaches and are attributed to to non-exhaustive extractions rather than limitations of the MS methods. Provided that sample preparation is carefully optimized for challenging matrices, the dMRM technique offers a powerful tool for high-throughput environmental analysis of PACs, enabling a single GC injection to streamline laboratory workflows and enhance analytical efficiency.

Fields of Study & Subjects

Analytical chemistry methods development Toxic Organic Pollutants Impact Analytical Chemistry and Chromatography

Publication details

Journal / source
Analytical Methods
Volume
18
Issue
7
Pages
1503–1512
Publication date
1 January 2026
Language
EN