A Bst-driven Cas12a cascade amplification strategy for microRNA detection
Abstract
M. Furthermore, the platform exhibited excellent sequence selectivity and was successfully applied to monitor miR-21 in both cell lysates and clinical serum samples. Considering its convenient operation, strong analytical performance, and simple readout mode, this method holds great potential for trace biomarker analysis in clinical diagnostics.
Fields of Study & Subjects
MicroRNA in disease regulation
Advanced biosensing and bioanalysis techniques
Biosensors and Analytical Detection
Publication details
- Journal / source
- Analytical Methods
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 4
- Pages
- 899–906
- Publication date
- 1 January 2026
- Language
- EN