SERS-assisted multivariate data analysis of the spectinomycin-Cu( ii ) complex released in blood serum from a stimuli-responsive drug carrier: in vitro kinetics modeling and pharmacodynamic analysis

Analytical Methods 2026

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Authors: Rayan Y. Mushtaq, Abdul Naman, Nasir Mehmood, Mohammed Alissa, Ghadah S. Abusalim, Musaad M Althobaiti, Minseok Kim
DOI: 10.1039/d5ay02042e
Cited by: 3
References: 73

Abstract

The cytotoxicity against the human liver cancer cell line (HepG2) and hemolytic analysis are also performed to validate the release kinetics in blood serum. The results indicate the improved antibacterial and biocompatible properties of SPM-Cu(II) released in the blood serum from the PVA/AgO hydrogel.

Fields of Study & Subjects

Protein Interaction Studies and Fluorescence Analysis Nanoparticle-Based Drug Delivery Gold and Silver Nanoparticles Synthesis and Applications

Publication details

Journal / source
Analytical Methods
Publisher
Royal Society of Chemistry (RSC)
Volume
18
Issue
13
Pages
2640–2658
Publication date
1 January 2026
Language
EN