Development and application of a tetra-ARMS PCR assay for detecting indel polymorphisms in the bovine PRNP gene

Analytical Methods 2026 Open access

Read full text
Authors: Ye Xu, Siyu Yang, Siling Ding, Ting Sheng Xu, Jian Ge, Weiming Xiao, Like Zhu, Feng Guan
DOI: 10.1039/d5ay02047f
Cited by: 0
References: 71

Abstract

Insertion/deletion (indel) polymorphisms in the promoter region (23 bp) and intron 1 (12 bp) of the bovine PRNP gene influence gene expression and susceptibility to bovine spongiform encephalopathy (BSE).

Fields of Study & Subjects

Prion Diseases and Protein Misfolding Molecular Biology Techniques and Applications Genetic and phenotypic traits in livestock

Publication details

Journal / source
Analytical Methods
Volume
18
Issue
10
Pages
2132–2141
Publication date
1 January 2026
Language
EN