SERS-based immunochromatographic assay with Au DTNB @Ag nanoparticles for the detection of ancient silk residues
Abstract
) as determined through Raman spectroscopy. The assay exhibited high specificity against interfering proteins and demonstrated consistent inter-batch reproducibility. When detecting real cultural relic samples, the immunochromatographic strip assay showed high accuracy and reliability, which was validated by indirect enzyme-linked immunosorbent assay (ELISA). Considering its high sensitivity, rapid analysis, and portability, the SERS ICA may provide a technologically advanced strategy for the on-site screening of silk residues in archaeological and museological contexts.
Fields of Study & Subjects
Silk-based biomaterials and applications
Gold and Silver Nanoparticles Synthesis and Applications
Biosensors and Analytical Detection
Publication details
- Journal / source
- Analytical Methods
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 9
- Pages
- 1948–1958
- Publication date
- 1 January 2026
- Language
- EN