A charge-reversal prodrug activated by tumor-acidity for selective cancer chemotherapy

Biomaterials Science 2026

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Authors: Bing Liu, Guanchun Wang, Quanjun Yang, Yang Yu, Yue Su, Wei Huang, Ping Wang, Deyue Yan, Ping Huang
DOI: 10.1039/d5bm01682g
Cited by: 0
References: 45

Abstract

studies in LoVo tumor-bearing mice showed significant tumor growth inhibition without significant systemic toxicity. This acid-triggered charge-reversal prodrug represents a promising strategy for selective cancer therapy.

Fields of Study & Subjects

Molecular Sensors and Ion Detection Supramolecular Self-Assembly in Materials Supramolecular Chemistry and Complexes

Publication details

Journal / source
Biomaterials Science
Volume
14
Issue
4
Pages
1052–1061
Publication date
1 January 2026
Language
EN