Synthesis of isoquinolin-1,4-diones via photocatalytic C(sp 2 )–C(sp 3 )-scission/oxidation of 4-(hydroxy(aryl)methyl)-isoquinolin-1(2 H )-ones

Chemical Communications 2026

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Authors: Taotao Zhao, Qianyi Liang, Keying Gu, Jiangbin Huang, Jiangbin Huang, Jinhui Hu, Jia‐Qiang Wu
DOI: 10.1039/d5cc03799a
Cited by: 0
References: 56

Abstract

This work reports a strategy for C(sp 2 )–C(sp 3 ) β-scission of 4-(hydroxy(aryl)methyl)-isoquinolinones, enabling the synthesis of C3-quaternary isoquinoline-1,4-diones and unlocking new sustainable pathways for structural diversification.

Fields of Study & Subjects

Synthesis and Biological Activity Catalytic C–H Functionalization Methods Traditional and Medicinal Uses of Annonaceae

Publication details

Journal / source
Chemical Communications
Volume
62
Issue
11
Pages
3522–3525
Publication date
1 January 2026
Language
EN