Polyethyleneimine-functionalized MXene as stable two-dimensional platforms for gene delivery systems

Chemical Communications 2026

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Authors: Farhan Hadi, Seoyeon Park, Tae-il Kim, Jae‐Min Oh
DOI: 10.1039/d5cc05910k
Cited by: 1
References: 14

Abstract

This study examined the influence of polyethyleneimine (PEI) molecular weight on the chemical bonding, colloidal behavior, pDNA loading, cytotoxicity, and cellular uptake of PEI-MXene hybrids. The hybrids showed reduced cytotoxicity compared with PEI, highlighting their potential as safe pDNA delivery systems.

Fields of Study & Subjects

MXene and MAX Phase Materials RNA Interference and Gene Delivery Graphene and Nanomaterials Applications

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
33
Pages
8510–8513
Publication date
1 January 2026
Language
EN