Direct observation and measurement of the average quantum methyl-tunneling frequency in a protein using T m -edited double electron–electron resonance EPR spectroscopy
Abstract
-edited DEER experiments arise from methyl tunnelling spin echo envelope modulation. Quantitative analysis yields an average methyl tunneling rate of 0.12 MHz, indicative of a high rotational barrier. These data provide the first direct observation of methyl tunneling in a protein by electron paramagnetic resonance.
Fields of Study & Subjects
Electron Spin Resonance Studies
Advanced NMR Techniques and Applications
Magnetism in coordination complexes
Publication details
- Journal / source
- Chemical Communications
- Volume
- 62
- Issue
- 13
- Pages
- 4112–4116
- Publication date
- 1 January 2026
- Language
- EN