NIR fluorescent probe for accurate diagnosis of acute kidney injury by monitoring leucine aminopeptidase
Abstract
Probe ECL could be activated by LAP with high sensitivity and excellent selectivity to emit NIR fluorescence. ECL-based fluorescence imaging of AKI achieved earlier diagnosis than serum marker determination and histological analysis of the kidneys. Furthermore, ECL was successfully used to monitor the progression of renal injury during breast cancer chemotherapy.
Fields of Study & Subjects
Nanoplatforms for cancer theranostics
Molecular Sensors and Ion Detection
Sulfur Compounds in Biology
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 13
- Pages
- 4080–4084
- Publication date
- 1 January 2026
- Language
- EN