β-barrels from short macrocyclic peptides

Chemical Communications 2026 Open access

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Authors: Viet Thuc Dang, Michael W. Martynowycz, Dan McElheny, Andy I. Nguyen
DOI: 10.1039/d5cc06640a
Cited by: 1
References: 29

Abstract

β-Barrels are ubiquitous motifs in proteins, and their design is highly challenging. Small peptides that form barrels are especially scarce. Here, we report barrels with the shortest stave, formed from 12-residue macrocyclic peptides.

Fields of Study & Subjects

Chemical Synthesis and Analysis Supramolecular Self-Assembly in Materials Biochemical and Structural Characterization

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
7
Pages
2304–2308
Publication date
1 January 2026
Language
EN