Synthesis of multifunctional lactam-substituted alkyl sulfones using rongalite as an electron donor, sulfone source, and C1 synthon

Chemical Communications 2026

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Authors: Hui-Ying Ren, Miao Wang, Shan Jiang, Zi-Xiang Bin, Xiao-Qing Li, Bangtun Zhao
DOI: 10.1039/d5cc06679d
Cited by: 1
References: 59

Abstract

A rongalite-mediated triple functionalization of N -allyl bromodifluoroacetamides with electron-rich heteroarenes via a sulfonylation/ethylation/heteroarylation sequence to prepare multifunctional lactam-substituted alkyl sulfones is presented.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Radical Photochemical Reactions Fluorine in Organic Chemistry

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
11
Pages
3606–3610
Publication date
1 January 2026
Language
EN