Palladium photocatalysis: a strategic approach for visible-light-mediated C(sp 2 )–H arylation
Abstract
) bonds through C-H bond functionalization. Herein, Pd-photoredox catalysis under blue LED irradiation was used to generate aryl (or heteroaryl) radicals from the corresponding redox-active iodoarenes and utilize them in C-H bond arylation. The key attraction lies in the wide functional group tolerance with impressive yield and the late-stage functionalization of natural products under mild reaction conditions. Operational simplicity and mechanistic evidence for photoinduced Pd catalysis illustrate the promise of this approach as a comprehensive platform for sustainable aryl-aryl cross-coupling.
Fields of Study & Subjects
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Chemical Communications
- Volume
- 62
- Issue
- 10
- Pages
- 3317–3320
- Publication date
- 1 January 2026
- Language
- EN