Tandem [2+4] annulation/aromatization reaction of yne–enones with o -sulfonamidobenzaldehydes
Abstract
-sulfonamidobenzaldehydes is reported, affording polyfunctionalized quinolines in moderate to high yields with a broad substrate scope. A plausible reaction mechanism is proposed, highlighting the potential of yne-enones to serve as versatile synthons for the development of new annulation strategies under phosphine catalysis.
Fields of Study & Subjects
Catalytic Alkyne Reactions
Cyclization and Aryne Chemistry
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Chemical Communications
- Volume
- 62
- Issue
- 16
- Pages
- 4774–4777
- Publication date
- 1 January 2026
- Language
- EN