Imaging of viscosity in ferroptosis-mediated acute alcoholic gastric injury and tumor models using an endoplasmic reticulum fluorescent probe

Chemical Communications 2026

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Authors: Hui Jun Wang, Ling Ma, Sijie Li, Rui Wang, Shaomin Shuang, Chuan Dong, Li Fan
DOI: 10.1039/d5cc06797a
Cited by: 3
References: 37

Abstract

We developed an endoplasmic reticulum (ER) fluorescent probe (ER-V) for viscosity detection. Importantly, using ER-V, we first revealed an increased ER viscosity in ferroptosis-mediated acute alcoholic gastric injury tissues, tumor mice, and even clinical patient tissue samples.

Fields of Study & Subjects

Ferroptosis and cancer prognosis Cancer Lipids and Metabolism Trace Elements in Health

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
12
Pages
3825–3829
Publication date
1 January 2026
Language
EN