RAA-CRISPR-HCR cascade amplification for ultrasensitive visual detection of African swine fever virus DNA

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Authors: Hongyu Wu, Shuhan Lin, Xiangcun Zuo, Weishi Hua, Tao Sun, Guoqing Shao, Fang Li, Dongming Zhao, Zhixin Feng, Dan Zhu, Lianhui Wang
Cited by: 2
References: 22

Abstract

An RAA-CRISPR-HCR (RCH) cascade amplification system was developed, which generates an ultrasensitive colorimetric response to low concentrations of African swine fever virus (ASFV) DNA with a detection limit of 1 copy µL −1 .

Fields of Study & Subjects

CRISPR and Genetic Engineering Animal Disease Management and Epidemiology Genetically Modified Organisms Research

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
14
Pages
4329–4332
Publication date
1 January 2026
Language
EN