Synthesis of CF 3 -indene-1-ol-fused pyridones possessing potent anticancer activities through C–H activation-initiated cascade annulation under redox-neutral conditions

Chemical Communications 2026

View at publisher
Authors: Shasha Ye, Jiayi Zou, Xueying Yang, Haiyun Xu, Chunhua Ma, Xinying Zhang, Xuesen Fan
DOI: 10.1039/d5cc06846k
Cited by: 4
References: 41

Abstract

Presented herein is an effective synthesis of CF 3 -indene-1-ol-fused pyridones based on a C–H activation-initiated cascade reaction of N -methoxyacrylamides with CF 3 -ynones.

Fields of Study & Subjects

Fluorine in Organic Chemistry Catalytic C–H Functionalization Methods Synthesis and Characterization of Pyrroles

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
14
Pages
4354–4357
Publication date
1 January 2026
Language
EN