Programming the photoelasticity of hydrogels for label-free mechanosensing by a simultaneous birefringence-stress reader (SiBRe)
Abstract
We present a strategy to program hydrogel photoelasticity using rationally designed force-transducing crosslinkers. Enabled by a simultaneous birefringence-stress reader (SiBRe), we show that stress-induced unfolding of flexible linkers can amplify the optical response, establishing a robust, dye-free platform for quantitative mechanosensing.
Fields of Study & Subjects
Hydrogels: synthesis
properties
applications
Advanced Materials and Mechanics
Cellular Mechanics and Interactions
Publication details
- Journal / source
- Chemical Communications
- Volume
- 62
- Issue
- 23
- Pages
- 6314–6318
- Publication date
- 1 January 2026
- Language
- EN