Cobalt-catalysed (4+3)-annulation of oxiranes with 4-vinyl indoles: stereospecific access to fused oxepinoindoles

Chemical Communications 2026

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Authors: Subhradeep Kar, Prabhat Kumar Maharana, Tharmalingam Punniyamurthy
DOI: 10.1039/d5cc06979c
Cited by: 0
References: 67

Abstract

A tandem C-C and C-O bond formation of oxiranes with 4-vinyl indoles has been accomplished under Co-catalysis following a base-promoted annulation to deliver fused oxepinoindole cores. The use of Co-catalysis, diastereoselectivity and chirality transfer (≥95% ee) are the important practical features.

Fields of Study & Subjects

Asymmetric Synthesis and Catalysis Catalytic Alkyne Reactions Synthesis of Indole Derivatives

Publication details

Journal / source
Chemical Communications
Volume
62
Issue
11
Pages
3550–3554
Publication date
1 January 2026
Language
EN