Iridium-catalyzed [5+1] cyclization of terminal alkynes with CF 3 -imidoyl sulfoxonium ylides to construct 2-trifluoroquinolines
Abstract
-imidoyl sulfoxonium ylides with terminal alkynes. A series of multi-substituted quinolines were successfully obtained in moderate to high yields under mild reaction conditions, exhibiting good functional group tolerance. Imidoyl sulfoxonium ylides were utilized as five-atom synthons, a new approach that enriches the diversity of accessible ring architectures.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Catalytic C–H Functionalization Methods
Click Chemistry and Applications
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 12
- Pages
- 3897–3901
- Publication date
- 1 January 2026
- Language
- EN