Crystal engineering of the cystic fibrosis drug ivacaftor: salts, solvates and hydrate forms with solubility and stability studies

CrystEngComm 2026

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Authors: Naga Prathyusha Doguparthi, Manimurugan Kanagavel, Sabiqa Samreen, Yaramala Navya, Yarasi Soujanya, Debasish Swain, Sunil Kumar Nechipadappu
DOI: 10.1039/d5ce01068c
Cited by: 0
References: 40

Abstract

Eight new multicomponent solid forms of IVA were prepared, the crystal structures were determined and evaluated their physicochemical properties.

Fields of Study & Subjects

Crystallization and Solubility Studies Crystallography and molecular interactions Drug Solubulity and Delivery Systems

Publication details

Journal / source
CrystEngComm
Volume
28
Issue
10
Pages
1621–1635
Publication date
1 January 2026
Language
EN