Mechanochemical synthesis of drug–drug eutectics of the anthelmintic drug, praziquantel, with NSAIDs

CrystEngComm 2026

View at publisher
Authors: Nitha Sadanandan, Abhina Mandodi, Cinu Winson, Indira S. Divya, Sunil Varughese
DOI: 10.1039/d5ce01149c
Cited by: 1
References: 29

Abstract

Mechanochemically synthesised praziquantel–NSAID eutectics, characterized by DSC, PXRD, HSM, and FT-IR, showed markedly enhanced solubility, faster dissolution, and strong tabletability, offering a scalable strategy to improve drug performance. Image partially created by AI using Google Gemini.

Fields of Study & Subjects

Crystallography and molecular interactions Drug Solubulity and Delivery Systems Crystallization and Solubility Studies

Publication details

Journal / source
CrystEngComm
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
14
Pages
2143–2150
Publication date
1 January 2026
Language
EN