Molecular dynamics investigation of the interaction between central-site chloride binding and proton transport in Ec CLC
Abstract
The presence of water molecules in the proton channel lowers the energy barriers of chloride translocation, and the conformation of the proton channel varies depending on the central-site chloride ion.
Fields of Study & Subjects
Ion Transport and Channel Regulation
Ion channel regulation and function
Molecular Sensors and Ion Detection
Publication details
- Journal / source
- Physical Chemistry Chemical Physics
- Volume
- 28
- Issue
- 5
- Pages
- 3656–3667
- Publication date
- 1 January 2026
- Language
- EN