A retrospective view on curly arrows revealed by the bonding evolution theory and non-covalent interactions: reaction mechanisms meet quantum foundations
Abstract
the corresponding transition structures and possible intermediates. Furthermore, this review examines various illustrative studies that offer the classic examples of internal proton transfer reaction, decarbonylation of unsaturated cyclic ketones, Mannich-type reactions, and thio-Claisen rearrangement. The analysis of the actual mechanism of these chemical reactions highlights the power of the ELF and NCI analysis to provide a physical basis for electron rearrangements along the reaction pathway. Finally, we address the current challenges and present perspectives for advancing the theoretical understanding and practical applications in this rapidly developing field.
Fields of Study & Subjects
Chemical Reaction Mechanisms
Advanced Chemical Physics Studies
Organic Chemistry Cycloaddition Reactions
Publication details
- Journal / source
- Physical Chemistry Chemical Physics
- Volume
- 28
- Issue
- 9
- Pages
- 5606–5628
- Publication date
- 1 January 2026
- Language
- EN