Coordination and oxidation properties of ZBTB20: CX 2 CX 12 HX 3 H-type zinc fingers

Dalton Transactions 2026

View at publisher
Authors: Hyunyong Kim, Yunha Hwang, Hyunwoo Jung, Jin Sung Cheong, Jiyeon Han, Seung Jae Lee
DOI: 10.1039/d5dt02032h
Cited by: 1
References: 57

Abstract

Zn 2+ coordination preserves the ββα fold and DNA-binding function of ZBTB20 zinc finger domains, whereas its absence leads to rapid cysteine oxidation, preventing metal coordination.

Fields of Study & Subjects

Trace Elements in Health RNA and protein synthesis mechanisms Genomics and Chromatin Dynamics

Publication details

Journal / source
Dalton Transactions
Publisher
Royal Society of Chemistry (RSC)
Volume
55
Issue
7
Pages
3127–3137
Publication date
1 January 2026
Language
EN