Synthesis, characterization and in vitro studies of metallacyclic derivatives of titanium( iv ) incorporated with Schiff's bases: DNA/BSA binding, computational aspects and cytotoxic potential

Dalton Transactions 2026

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Authors: Mahabarathi Subramaniyan, Sathish Thanigachalam, Shivabasayya V. Salimath, Selva Kumar Ramasamy, Kevin George, Madhvesh Pathak
DOI: 10.1039/d5dt02277k
Cited by: 2
References: 74

Abstract

Four titanium( iv ) derivatives were synthesized, and two characterized by SC-XRD. These complexes have been found to exhibit higher activity for DNA/BSA binding as well as high potency for cytotoxicity against the MCF-7 and HT-29 cancer cell lines.

Fields of Study & Subjects

Metal complexes synthesis and properties Ferrocene Chemistry and Applications Organometallic Compounds Synthesis and Characterization

Publication details

Journal / source
Dalton Transactions
Publisher
Royal Society of Chemistry (RSC)
Volume
55
Issue
4
Pages
1806–1832
Publication date
1 January 2026
Language
EN