Structure–bioactivity relationship in copper( ii ) complexes with new halogenated coumarin derivatives

Dalton Transactions 2026

View at publisher
Authors: Jakub Kurjan, Zuzana Jendželovská, Viktória Dečmanová, Rastislav Jendželovský, Nikolina Kastratović, Vladislav Volarevic, Lukáš Smolko, Romana Smolková, Miroslava Litecká, Anton Zubrík, Dávid Jáger, Rastislav Varhač
+1 more Ivan Potočňák
DOI: 10.1039/d5dt02641e
Cited by: 1
References: 65

Abstract

antitumor studies were carried out, including cell proliferation assays, quantification of cell number and viability, and flow cytometry analyses. Moreover, comprehensive evaluations such as Hirshfeld surface analysis, DNA-binding affinity (using fluorescence competitive dye displacement assay with ethidium bromide and viscometry), human serum albumin (HSA) interaction, antioxidant activity, and lipophilicity assessments were performed to further explore their biomedical potential.

Fields of Study & Subjects

Metal complexes synthesis and properties Metal-Organic Frameworks: Synthesis and Applications Molecular Sensors and Ion Detection

Publication details

Journal / source
Dalton Transactions
Publisher
Royal Society of Chemistry (RSC)
Volume
55
Issue
15
Pages
6191–6211
Publication date
1 January 2026
Language
EN