Investigation of the photophysical, photochemical, and multifunctional biological properties of fluorinated zinc( ii ) phthalocyanine functionalized with carboxylic acid

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Authors: Gülru Özay, Mukaddes Özçeşmeci, Seyma Isik, Ceren Can Karanlık, Ayfer Kalkan Burat, Alı Erdoğmuş, Sadin Özdemir, Gülay Giray, M. Serkan Yalçın, Müge Serhatlı, Esin Hamuryudan
Cited by: 0
References: 81

Abstract

. Importantly, the biocompatibility of compound 2 was confirmed in L929 fibroblast cells. While it exhibited concentration-dependent cytotoxicity in the dark, under light irradiation, cell viability remained close to or above the thresholds defined by ISO 10993-5 for non-cytotoxicity. As a result, compound 2 is a multifunctional phthalocyanine derivative that combines diverse biological activities with a safety profile, supporting its potential as a promising candidate for biomedical applications.

Fields of Study & Subjects

Porphyrin and Phthalocyanine Chemistry Photodynamic Therapy Research Studies Porphyrin Metabolism and Disorders

Publication details

Journal / source
Dalton Transactions
Volume
55
Issue
5
Pages
2100–2110
Publication date
1 January 2026
Language
EN