Comparative solution study of imidazole-derived thiosemicarbazone complexes: effects of methylation and aromatic conjugation on the redox properties, anticancer, and antibacterial activity

Dalton Transactions 2026 Open access

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Authors: Tatsiana V. Petrasheuskaya, Márton A. Kiss, P. Rapta, Csenge Anna Fónay, Nóra Veronica May, Gabriella Spengler, Éva Frank, Eva A. Enyedy
DOI: 10.1039/d5dt02939b
Cited by: 3
References: 62

Abstract

-imidazole-TSC demonstrated the greatest potency, while the benzimidazole-TSC complex also exhibited pronounced activity. Methyl substitution and aromatic conjugation were found to substantially improve the cytotoxic effect.

Fields of Study & Subjects

Metal complexes synthesis and properties Metal-Catalyzed Oxygenation Mechanisms Metal-Organic Frameworks: Synthesis and Applications

Publication details

Journal / source
Dalton Transactions
Publisher
Royal Society of Chemistry (RSC)
Volume
55
Issue
10
Pages
4269–4287
Publication date
1 January 2026
Language
EN