Chlorogenic acid improves DSS-induced colitis in mice by regulating the gut microbiota

Food & Function 2026

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Authors: Qinqiu Zhang, Shixiong Deng, Yiya Sun, Jiajun Lv, Danka Bukvički, Yaowen Liu, Qing Zhang, Derong Lin, wen Qin
DOI: 10.1039/d5fo02858b
Cited by: 4
References: 59

Abstract

. CGA (100 mg per kg body weight) supplementation also reversed the generation of short-chain fatty acids (SCFAs), especially propionic acid, butyric acid, isobutyric acid and 4-methylvaleric acid. Consequently, these findings demonstrated that supplementation of CGA attenuated the severity of intestinal inflammation by ameliorating gut microbiota dysbiosis and promoting the growth of butyrate-producing gut microbiota.

Fields of Study & Subjects

Gut microbiota and health Inflammatory Bowel Disease Barrier Structure and Function Studies

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
3
Pages
1645–1659
Publication date
1 January 2026
Language
EN