Bioaccessible sulforaphane attenuates oxidative stress-driven parainflammation in intestinal epithelial cells
Abstract
) evidenced a significant anti-inflammatory capacity, which is, to some extent, independent of the weaker capacity to prevent oxidative stress. This result was further confirmed by implementing a model system, which analysed COX-2 expression and the synthesis of isoprostanoids at decreasing concentrations of SFN, starting at the bioaccessible level. The main results obtained emphasise the value of broccoli stalks as a source of antioxidant and anti-inflammatory compounds at operative concentrations in the intestinal lumen and encourage their consideration as a valuable ingredient for health-promoting co-products.
Fields of Study & Subjects
Genomics
phytochemicals
and oxidative stress
Curcumin's Biomedical Applications
Phytochemicals and Antioxidant Activities
Publication details
- Journal / source
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 5
- Pages
- 2550–2559
- Publication date
- 1 January 2026
- Language
- EN