Lacticaseibacillus rhamnosus DACN152 effectively ameliorated letrozole-induced polycystic ovary syndrome: sex hormone homeostasis, microbiota and metabolite profiles

Food & Function 2026

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Authors: Xiaoyong Chen, Xiao Liu, Jiajing Wang, Amel Ahmed Ibrahim, Zsolt Zalán, Huayi Suo
DOI: 10.1039/d5fo03870g
Cited by: 2
References: 34

Abstract

. Serum metabolomic analysis revealed elevated levels of bile acids, including chenodeoxycholic acid (CDCA), taurocholic acid (TCA), taurochenodeoxycholic acid (TCDCA), and cholic acid (CA). Collectively, these findings provide a theoretical basis for the development of probiotic-functional foods for PCOS.

Fields of Study & Subjects

Ovarian function and disorders Reproductive System and Pregnancy Reproductive tract infections research

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
6
Pages
2745–2758
Publication date
1 January 2026
Language
EN