Akkermansia muciniphila alleviates diabetic cognitive impairment by inhibiting NLRP3 inflammasome activation and ameliorating hippocampal synaptic defects

Food & Function 2026

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Authors: Yage Du, Yu An, Zhaoming Cao, Guangyi Xu, Ming Chu, Ye Lu
DOI: 10.1039/d5fo03902a
Cited by: 1
References: 58

Abstract

in alleviating DCI by inhibiting the activation of the NLRP3 inflammasome and ameliorating hippocampal synaptic defects. This study provides insights into the underlying mechanisms and presents a novel avenue for probiotic-based treatment of DCI.

Fields of Study & Subjects

Inflammasome and immune disorders Gut microbiota and health Oral microbiology and periodontitis research

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
12
Pages
5738–5755
Publication date
1 January 2026
Language
EN